We've been having a good run of Mini-ITX cases lately, but most of those cases are designed to still be able to support what are essentially fully-powered systems: standard voltage CPUs, dedicated graphics cards, an optical drive and multiple storage drives. Yet part of the charm of Mini-ITX is that it's capable of fitting into a much smaller space than even a Micro-ATX board theoretically could. If you're gunning just to produce a system that's very small and very efficient, but you don't want to just use someone else's build, a Mini-ITX board and the right enclosure can have you covered.
That's where the Antec ISK 110 VESA comes in. This case is about as small as it gets, and includes the necessary hardware to actually mount it to the back of a monitor. Antec has trimmed about as much fat as you could conceivably hope to trim; there's enough room for a Mini-ITX board, two 2.5" drives, and that's it. It includes an external 90-watt power supply and just enough internal power circuitry to drive low-to-moderate power hardware. With so little room to work in, did Antec make the right decisions, or was there still more they could do ?